Research Articles
Probing Biofilm Nanomechanics with Atomic Force Microscopy: From Fundamental Principles to Clinical Applications
This article provides a comprehensive examination of how Atomic Force Microscopy (AFM) is revolutionizing the quantification of biofilm nanomechanical properties.
Spatial Heterogeneity in Biofilms: A Microfluidic Approach for Quantitative Analysis
This article explores the transformative role of microfluidic technologies in quantifying the spatial and temporal heterogeneity of bacterial biofilms.
Host Gene Expression Signatures for Bacterial vs Viral Infection: From Foundational Biology to Clinical Diagnostics
Accurate discrimination between bacterial and viral infections is a critical unmet need in clinical medicine, directly impacting antibiotic stewardship and patient outcomes.
Absolute Bacterial Quantification by 16S qPCR: A Complete Guide from Fundamentals to Clinical Application
This article provides a comprehensive resource for researchers and drug development professionals on implementing absolute bacterial quantification using 16S qPCR.
MALDI-TOF MS for Bacterial Identification in Raw Milk: A Comprehensive Guide for Biomedical Research and Quality Control
This article provides a comprehensive overview of the application of Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) for bacterial identification in raw milk, a critical matrix for both food...
Bacterial Foraging Optimization: Theory, Applications, and Advances for Biomedical Research
This article provides a comprehensive examination of Bacterial Foraging Optimization (BFO) algorithms, a class of swarm intelligence techniques inspired by Escherichia coli foraging behavior.
Host Gene Expression Profiling: A New Frontier for Precision Diagnosis of Bacterial Infections
The rapid and accurate discrimination of bacterial infections from viral etiologies and non-infectious inflammatory syndromes is a critical challenge in clinical practice, directly impacting antimicrobial stewardship and patient outcomes.
Soil Microbial Community Dynamics: Drivers, Functions, and Implications for Ecosystem Health
This article synthesizes current research on soil microbial community dynamics, a critical frontier in environmental and soil science.
The Viable But Non-Culturable (VBNC) State in Bacteria: A Comprehensive Guide to Mechanisms, Detection, and Clinical Implications
This article provides a comprehensive analysis of the bacterial Viable But Non-Culturable (VBNC) state, a dormant survival strategy with profound implications for public health, clinical diagnostics, and drug development.
Quorum Sensing in Biofilm Maturation: Mechanisms, Therapeutic Targeting, and Future Directions
This article provides a comprehensive analysis of the critical role bacterial quorum sensing (QS) plays in the maturation and virulence of biofilms, a major contributor to chronic infections and antimicrobial...